The winter 2021 issue of Leap Magazine for Johns Hopkins Medicine Division of Rheumatology features “Out of the Darkness of a Pandemic: Flashes of Insight:” a therapeutic discovery that may help patients with severe inflammatory complications of Covid-19. Other stories include the long-haul recovery of some lyme disease patients, a new culprit in Sjogren’s Syndrome, and an examination of why Sjogren’s is more common in women than men. Cover story illustration by Brian Stauffer.